Descrição
PN: SC-374649
Marca: Santa Cruz
Rab GDI α/β Antibody (E-5) is a high quality monoclonal Rab GDI alpha / beta antibody (also designated Rab GDI α/β antibody) suitable for the detection of the Rab GDI alpha / beta protein of mouse, rat and human origin. Rab GDI α/β Antibody (E-5) is available as both the non-conjugated anti-Rab GDI alpha / beta antibody form, as well as multiple conjugated forms of anti-Rab GDI alpha / beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1–3). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI α (also known as XAP-4) and Rab GDI β. While the mammalian Rab GDI β-genes are ubiquitously expressed, the Rab GDI α genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms..
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
